When Tosh goes missing, Daffy and Lola team up to find him. Meanwhile, Bugs tries to catch a large African sand spider that got into his house. Daffy and Lola create a missing poster for Tosh, but ended up picturing Speedy. Tosh is revealed to have only taken a walk; the note he left was overlooked by Daffy, who was using the same notepad to write clues. Bugs successfully releasing bug poison to be rid of the spider; however, Gossamer ends up ruining everything by saying his harmless pet spider, which only looks like an African sand spider, has gone missing. Bugs saved the spider, but finds Gossamer had located his true pet; the spider bites Bugs, paralyzing him for a time.
At Pizzariba!, Daffy and Lola are treating Bugs, who has mostly recovered from the poisoning. They are then left wondering where Speedy is; Yosemite Sam saw their accidental poser and kidnapped Speedy to be taken to Mac for the reward for the previously missing Tosh.